You can use cached credentials for any or all of the following:
Cached passwords for client access
Use cached passwords to give users access to domain resources using their own Windows credentials. This option is needed only when users log into the server without using their Windows credentials (for example using public key authentication). Without cached credentials, users who log in with public key authentication have access to folders on local drives, but don't have access to network resources. For more information, see Record and Use Cached Credentials.
SFTP directories and mapped drives
Use a specified account to connect to SFTP-accessible network resources or mapped drives. This option allows you to provide access that wouldn't be available to a user based on that user's own Windows account privileges.
Active Directory access
Use a specified account to give the server access to Active Directory. The server uses this account when it queries Windows Active Directory for user attributes and group membership. For more information, see Active Directory Access Pane.
Reflection Gateway user access account
Use a specified account to provide access to Reflection for Secure IT Gateway users. Reflection Gateway users run under the privileges of the specified account. This option is relevant only if you have installed and configured Reflection for Secure IT Gateway and have enabled connections from Reflection Gateway Users on the Reflection Gateway Users Pane.